A regioselective cycloaddition route to isoxazoleboronic esters

被引：53

作者：

Davies, MW

Wybrow, RAJ

Johnson, CN

Harrity, JPA ^{[1
]}

机构：

[1] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England

[2] GlaxoSmithKline, Med Chem, Harlow CM19 5AW, Essex, England

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 17期

关键词：

D O I：

10.1039/b103319k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Alkynylboronates participate in 1,3-dipolar cycloaddition reactions with nitrile oxides to provide isoxazoleboronic esters with excellent levels of regiocontrol; additionally, these potentially valuable synthetic intermediates have been shown to participate efficiently in Suzuki coupling reactions.

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收藏

页码：1558 / 1559

页数：2

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