Novel β-cyclodextrin modified CdTe quantum dots as fluorescence nanosensor for acetylsalicylic acid and metabolites

被引：28

作者：

Algarra, M. ^{[2
]}

Campos, B. B. ^{[1
]}

Aguiar, F. R. ^{[1
]}

Rodriguez-Borges, J. E. ^{[1
]}

Esteves da Silva, J. C. G. ^{[1
]}

机构：

[1] Univ Porto, Ctr Invest Quim CIQ UP, Fac Ciencias, P-169007 Oporto, Portugal

[2] Univ Porto, Fac Ciencias, Ctr Geol Porto, P-4169007 Oporto, Portugal

来源：

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2012年 / 32卷 / 04期

关键词：

Acetyl salicylic acid; Nanosensor; thiol-beta-cyclodextrin; CdTe quantum dots; MOLECULAR RECOGNITION; SALICYLIC-ACID; NANOCRYSTALS; DECOMPOSITION; BEHAVIOR; ASPIRIN; SURFACE; PROBES; CELLS; WATER;

D O I：

10.1016/j.msec.2012.01.028

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

082905 [生物质能源与材料]; 100103 [病原生物学];

摘要：

beta-Cyclodextrin was modified with 11-[(ethoxycarbonyl)thio]undecanoic acid and used as a capping agent, together with mercaptosuccinic acid, to prepare water-stable CdTe quantum dots. The water soluble quantum dot obtained displays fluorescence with a maximum emission at 425 nm (under excitation at 300 nm) with lifetimes of 0.53, 4.8, 181, and 44.1 ns, respectively. The S-beta CD-MSA-CdTe can act as a nanoprobe that is due to the affinity of the cyclodextrin moiety for selected substances such as acetylsalicylic acid (ASA) and its metabolites as foreign species. The fluorescence of the S-beta CD-MSA-CdTe is enhanced on addition of ASA. Linear calibration plots are observed with ASA in concentrations between 0 and 1 mg/l, with a limit of detection at 8.5 x 10(-9) mol/1 (1.5 ng/ml) and a precision as relative standard deviation of 1% (0.05 mg/l). The interference effect of certain compounds as ascorbic acid and its main metabolites such as salicylic, gentisic and salicyluric acid upon the obtained procedure was studied. (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：799 / 803

页数：5

共 41 条

[1]

Semiconductor nanocrystals as fluorescent biological labels [J].

Bruchez, M ;

Moronne, M ;

Gin, P ;

Weiss, S ;

Alivisatos, AP .

SCIENCE, 1998, 281 (5385) :2013-2016

[2]

Fluorescent Properties of a Hybrid Cadmium Sulfide-Dendrimer Nanocomposite and its Quenching with Nitromethane [J].

Campos, Bruno B. ;

Algarra, Manuel ;

Esteves da Silva, Joaquim C. G. .

JOURNAL OF FLUORESCENCE, 2010, 20 (01) :143-151

[3]

Mercury(II) sensing based on the quenching of fluorescence of CdS-dendrimer nanocomposites [J].

Campos, Bruno B. ;

Algarra, Manuel ;

Alonso, Beatriz ;

Casado, Carmen M. ;

Esteves da Silva, Joaquim C. G. .

ANALYST, 2009, 134 (12) :2447-2452

[4]

Functionalized cadmium sulfide quantum dots as fluorescence probe for silver ion determination [J].

Chen, JL ;

Zhu, CQ .

ANALYTICA CHIMICA ACTA, 2005, 546 (02) :147-153

[5]

Luminescent CdS quantum dots as selective ion probes [J].

Chen, YF ;

Rosenzweig, Z .

ANALYTICAL CHEMISTRY, 2002, 74 (19) :5132-5138

[6]

C-S STRETCHING FREQUENCY IN THIOL ACIDS AND ESTERS [J].

CROWDER, GA .

APPLIED SPECTROSCOPY, 1972, 26 (04) :486-&

[7]

da Silva JCGE, 1998, ANALYST, V123, P2067

[8]

New insights regarding the cyclodextrin/AAS self-assembly: A molar ratio dependent system [J].

Denadai, Angelo M. L. ;

Santoro, Marcelo M. ;

Texeira, Alvaro V. ;

Sinisterra, Ruben D. .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2010, 30 (03) :417-422

[9]

Capped cyclodextrins [J].

Engeldinger, E ;

Armspach, D ;

Matt, D .

CHEMICAL REVIEWS, 2003, 103 (11) :4147-4173

[10]

Strongly photoluminescent CdTe nanocrystals by proper surface modification [J].

Gao, MY ;

Kirstein, S ;

Möhwald, H ;

Rogach, AL ;

Kornowski, A ;

Eychmüller, A ;

Weller, H .

JOURNAL OF PHYSICAL CHEMISTRY B, 1998, 102 (43) :8360-8363

← 1 2 3 4 5 →