Adiponectin responses to continuous and progressively intense intermittent exercise

被引:115
作者
Kraemer, RR [1 ]
Aboudehen, KS
Carruth, AK
Durand, RJ
Acevedo, EO
Hebert, EP
Johnson, LG
Castracane, VD
机构
[1] SE Louisiana Univ, Dept Kinesiol & Hlth Studies, Hammond, LA 70402 USA
[2] Pennington Biomed Res Ctr, Hlth & Fitness Ctr, Baton Rouge, LA USA
[3] Univ Mississippi, Div Exercise Sci, University, MS 38677 USA
[4] Louisiana State Univ, Dept Kinesiol, Baton Rouge, LA 70803 USA
[5] Texas Tech Univ, Hlth Sci Ctr, Dept Obstet & Gynecol, Amarillo, TX USA
[6] Texas Tech Univ, Hlth Sci Ctr, Womens Hlth Res Inst Amarillo, Amarillo, TX USA
关键词
running; adipocytokine; insulin; glucose;
D O I
10.1249/01.MSS.0000079072.23998.F3
中图分类号
G8 [体育];
学科分类号
04 [教育学]; 0403 [体育学];
摘要
Purpose: Adiponectin is a recently discovered adipocyte protein that is lower in patients with coronary artery disease and in Type 11 diabetics who have insulin resistance. Regular exercise is known to be a preventative factor in the development of atherosclerosis and Type 11 diabetes. Acute exercise increases insulin sensitivity; however, it also increases beta-adrenergic and glucocorticoid activities that may suppress adiponectin expression. Two experiments were conducted to determine whether acute exercise affects adiponectin concentrations. Methods: In the first experiment, six healthy male subjects completed 30 min of heavy continuous running exercise at 79% of VO2max. In the second experiment, well-trained runners completed strenuous intermittent exercise consisting of treadmill running at 60, 75, 90, and 100% VO2max. A resting control trial for the second experiment was also conducted. Results: Glucose and insulin were not altered significantly in the first experiment, but both increased significantly (P < 0.05) in the second experiment. A significant increase (P < 0.05) in adiponectin in the first experiment was no longer significant after correction for plasma volumes shifts. In the second experiment, there were significant (P < 0.05) changes in adiponectin concentrations over time but not a significant difference between adiponectin responses in exercise and control trials. Conclusions: The data suggest that 30 min of heavy continuous running or more strenuous intermittent running does not stimulate an increase in production and release of adiponectin, and small increases in adiponectin concentrations resulting from the exercise may be attributed to normal plasma volume shifts.
引用
收藏
页码:1320 / 1325
页数:6
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