The neurobiology and genetics of impulse control disorders: Relationships to drug addictions

被引：307

作者：

Brewer, Judson A. ^{[1
]}

Potenza, Marc N. ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06520 USA

来源：

BIOCHEMICAL PHARMACOLOGY | 2008年 / 75卷 / 01期

关键词：

addiction; impulse control disorders; pathological gambling; brain imaging; genetics;

D O I：

10.1016/j.bcp.2007.06.043

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

Impulse control disorders (ICDs), including pathological gambling, trichotillomania, kleptomania and others, have been conceptualized to lie along an impulsive-compulsive spectrum. Recent data have suggested that these disorders may be considered addictions. Here, we review the genetic and neuropathological bases of the impulse control disorders and consider the disorders within these non-mutually exclusive frameworks. (C) 2007 Elsevier Inc. All rights reserved.

引用

页码：63 / 75

页数：13

共 202 条

[1]

Resting regional cerebral blood flow and gambling task performance in cocaine-dependent subjects and healthy comparison subjects [J].

Adinoff, B ;

Devous, MD ;

Cooper, DB ;

Best, SE ;

Chandler, P ;

Harris, T ;

Cervin, CA ;

Cullum, CM .

AMERICAN JOURNAL OF PSYCHIATRY, 2003, 160 (10) :1892-1894

[2]

*AM PSYCH ASS COMM, 2000, DIAGN STAT MAN MENT

[3]

[Anonymous], BIOL PSYCHIAT

[4]

Baker DA, 2002, J NEUROSCI, V22, P9134

[5]

Drug addiction: the neurobiology of disrupted self-control [J].

Baler, Ruben D. ;

Volkow, Nora D. .

TRENDS IN MOLECULAR MEDICINE, 2006, 12 (12) :559-566

[6]

EFFECTS OF INTRAVENOUS COCAINE ON PLASMA-CORTISOL AND PROLACTIN IN HUMAN COCAINE ABUSERS [J].

BAUMANN, MH ;

GENDRON, TM ;

BECKETTS, KM ;

HENNINGFIELD, JE ;

GORELICK, DA ;

ROTHMAN, RB .

BIOLOGICAL PSYCHIATRY, 1995, 38 (11) :751-755

[7]

Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective [J].

Bechara, A .

NATURE NEUROSCIENCE, 2005, 8 (11) :1458-1463

[8]

Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences [J].

Bechara, A ;

Damasio, H .

NEUROPSYCHOLOGIA, 2002, 40 (10) :1675-1689

[9]

Bechara A, 2001, Semin Clin Neuropsychiatry, V6, P205, DOI 10.1053/scnp.2001.22927

[10]

INSENSITIVITY TO FUTURE CONSEQUENCES FOLLOWING DAMAGE TO HUMAN PREFRONTAL CORTEX [J].

BECHARA, A ;

DAMASIO, AR ;

DAMASIO, H ;

ANDERSON, SW .

COGNITION, 1994, 50 (1-3) :7-15

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