Notch signaling in lymphocyte development

被引：47

作者：

Anderson, AC ^{[1
]}

Robey, EA ^{[1
]}

Huang, YH ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2001年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(00)00232-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Signaling through Notch has been implicated in many cell-fate decisions during lymphocyte development. Recent studies have provided new clues - and raised new controversies - regarding the exact role that Notch signaling plays in the commitment of cells to the T-cell lineage. Progress has also been made in deducing the transcriptional program induced by Notch and the mechanism of oncogenic transformation by Notch in lymphocytes.

引用

页码：554 / 560

页数：7

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