Death receptors and apoptosis

被引：61

作者：

Contassot, Emmanuel

Gaide, Olivier

French, Lars E.

机构：

[1] Univ Zurich Hosp, Dept Dermatol, CH-8091 Zurich, Switzerland

[2] Ctr Med Univ Geneva, Dept Pathol, Geneva, Switzerland

[3] Ctr Med Univ Geneva, Dept Immunol, Geneva, Switzerland

[4] Ctr Med Univ Geneva, Dept Dermatol, Geneva, Switzerland

[5] Univ Hosp Geneva, Geneva, Switzerland

来源：

DERMATOLOGIC CLINICS | 2007年 / 25卷 / 04期

关键词：

D O I：

10.1016/j.det.2007.06.010

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 [皮肤病与性病学];

摘要：

Interactions between death receptors from the tumor necrosis factor superfamily and their ligands play a crucial role in the development and the integrity of the epidermis. The major consequence resulting from death receptor targeting is apoptosis. Evidence for dysregulation of death receptor signaling associated with the pathogenesis of selected cutaneous diseases, including toxic epidermal necrolysis, graft versus host disease, and skin cancer, are reviewed herein.

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页码：487 / +

页数：16

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