GeneSplicer: a new computational method for splice site prediction

被引：460

作者：

Pertea, M ^{[1
]}

Lin, XY ^{[1
]}

Salzberg, SL ^{[1
]}

机构：

[1] Inst Genom Res, Rockville, MD 20850 USA

来源：

NUCLEIC ACIDS RESEARCH | 2001年 / 29卷 / 05期

关键词：

D O I：

10.1093/nar/29.5.1185

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes, The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and SpliceView. In each case GeneSplicer performed comparably to the best alternative, in terms of both accuracy and computational efficiency.

引用

页码：1185 / 1190

页数：6

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