Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review

被引:51
作者
Virlan, Maria Justina Roxana [1 ]
Miricescu, Daniela [1 ]
Totan, Alexandra [1 ]
Greabu, Maria [1 ]
Tanase, Cristiana [2 ,3 ]
Sabliov, Cristina M. [4 ,5 ]
Caruntu, Constantin [6 ]
Calenic, Bogdan [1 ,2 ]
机构
[1] Univ Med & Pharm Carol Davila, Fac Dent, Dept Biochem, Bucharest 050474, Romania
[2] Victor Babes Natl Inst Pathol, Biochem Prote Dept, Bucharest 050096, Romania
[3] Titu Maiorescu Univ, Fac Med, Bucharest 040441, Romania
[4] Louisiana State Univ, Dept Agr & Biol Engn, Baton Rouge, LA 70803 USA
[5] LSU Ag Ctr, Baton Rouge, LA 70803 USA
[6] Carol Davila Univ Med & Pharm, Dept Physiol, Bucharest 050474, Romania
关键词
CO-GLYCOLIC ACID; GUIDED BONE REGENERATION; IN-VITRO; TITANIUM IMPLANTS; PLGA NANOPARTICLES; GROWTH-FACTOR; STEM-CELLS; BIODEGRADABLE MICROSPHERES; POLYMERIC NANOPARTICLES; TISSUE REGENERATION;
D O I
10.1155/2015/525832
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
Poly(lactic-co-glycolic acid) or PLGA is a biodegradable polymer used in a wide range of medical applications. Specifically PLGA materials are also developed for the dental field in the form of scaffolds, films, membranes, microparticles, or nanoparticles. PLGA membranes have been studied with promising results, either alone or combined with other materials in bone healing procedures. PLGA scaffolds have been used to regenerate damaged tissues together with stem cell-based therapy. There is solid evidence that the development of PLGA microparticles and nanoparticles may be beneficial to a wide range of dental fields such as endodontic therapy, dental caries, dental surgery, dental implants, or periodontology. The aim of the current paper was to review the recent advances in PLGA materials and their potential uses in the dental field.
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页数:12
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