Deoxyribozyme-based ligase logic gates and their initial circuits

被引：119

作者：

Stojanovic, MN

Semova, S

Kolpashchikov, D

Macdonald, J

Morgan, C

Stefanovic, D

机构：

[1] Columbia Univ, Dept Med, Div Clin Pharmacol & Expt Therapeut, New York, NY 10032 USA

[2] Univ New Mexico, Dept Comp Sci, Albuquerque, NM 87131 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 19期

关键词：

D O I：

10.1021/ja043003a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A complete set (YES, NOT, AND, and ANDNOT) of molecular scale logic gates based on ligase deoxyribozymes was constructed. The activity of these gates was visualized through the formation of cascades with downstream phosphodieseterase YES gates, which performed fluorogenic cleavage. Copyright © 2005 American Chemical Society.

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收藏

页码：6914 / 6915

页数：2

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