The oxygen sensor PHD3 limits glycolysis under hypoxia via direct binding to pyruvate kinase

被引:28
作者
Chen, Nan [1 ,2 ,3 ]
Rinner, Oliver [1 ,2 ]
Czernik, Dominika [1 ,2 ]
Nytko, Katarzyna J. [4 ,5 ]
Zheng, Dan [1 ,2 ]
Stiehl, Daniel P. [4 ,5 ]
Zamboni, Nicola [1 ,2 ]
Gstaiger, Matthias [1 ,2 ]
Frei, Christian [1 ,2 ]
机构
[1] ETH, Dept Biol, CH-8093 Zurich, Switzerland
[2] CC SPMD, CH-8093 Zurich, Switzerland
[3] Chinese Acad Sci, Shanghai Inst Appl Phys, Phys Biol Lab, Shanghai 201800, Peoples R China
[4] Univ Zurich, Inst Physiol, CH-8057 Zurich, Switzerland
[5] Zurich Ctr Integrat Human Physiol ZIHP, CH-8057 Zurich, Switzerland
关键词
PROLYL HYDROXYLASE;
D O I
10.1038/cr.2011.66
中图分类号
Q2 [细胞生物学];
学科分类号
071013 [干细胞生物学];
摘要
引用
收藏
页码:983 / 986
页数:4
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