Uterine receptivity to human embryonic implantation: Histology, biomarkers, and transcriptomics

被引：110

作者：

Aghajanova, L. ^{[1
]}

Hamilton, A. E. ^{[1
]}

Giudice, L. C. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, San Francisco, CA 94143 USA

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2008年 / 19卷 / 02期

关键词：

human implantation; endometrium; microarray; implantation markers;

D O I：

10.1016/j.semcdb.2007.10.008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Embryonic implantation is a dynamic process of paracrine interactions between the maternal compartment and the conceptus and involves a receptive endometrium and a developmentally competent blastocyst. Herein, we review histology, clinical approaches, and the promise of transcriptomics in elucidating mechanisms underlying implantation and development of biomarkers of uterine receptivity-with an eye to diagnose and treat implantation-based disorders of miscarriage, fetal growth restriction, pre-eclampsia, and infertility. Published by Elsevier Ltd.

引用

页码：204 / 211

页数：8

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