Phosphatidic acid: an emerging plant lipid second messenger

被引:315
作者
Munnik, T [1 ]
机构
[1] Univ Amsterdam, Swammerdam Inst Life Sci, Dept Plant Physiol, NL-1098 SM Amsterdam, Netherlands
关键词
D O I
10.1016/S1360-1385(01)01918-5
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Evidence is accumulating that phosphatidic acid is a second messenger. Its level increases within minutes of a wide variety of stress treatments including ethylene, wounding, pathogen elicitors, osmotic and oxidative stress, and abscisic acid. Enhanced signal levels are rapidly attenuated by phosphorylating phosphatidic acid to diacylglycerol pyrophosphate. Phosphatidic acid is the product of two signalling pathways, those of phospholipases C and D, the former in combination with diacylglycerol kinase. Families of these genes are now being cloned from plants. Several downstream targets of phosphatidic acid have been identified, including protein kinases and ion channels.
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页码:227 / 233
页数:7
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