Rapidly evolving hepatitis C virus-related cirrhosis in a human immunodeficiency virus-infected patient receiving triple antiretroviral therapy

被引：100

作者：

Zylberberg, H

Pialoux, G

Carnot, P

Landau, A

Bréchot, C

Pol, S

机构：

[1] Hop Necker Enfants Malad, Unite Hepatol, F-75015 Paris, France

[2] Hop Inst Pasteur, Paris, France

[3] Hop Laennec, Lab Anatomopathol, Paris, France

[4] INSERM, U370, Paris, France

来源：

CLINICAL INFECTIOUS DISEASES | 1998年 / 27卷 / 05期

关键词：

D O I：

10.1086/514987

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Triple antiretroviral therapy combining reverse transcriptase and protease inhibitors modifies the prognosis of human immunodeficiency virus (HIV) infection, with dramatic improvement in immune status. The precise impact, if any, of anti-HIV triple therapy on hepatitis C virus (HCV) infection is unknown. We describe an unusual case of rapidly evolving HCV-related cirrhosis that paralleled restoration of immune status in an HIV-infected patient and discuss the possible link between such a severe course of hepatitis C and anti-HIV triple therapy.

引用

页码：1255 / 1258

页数：4

共 14 条

[1] HEPATITIS-C VIRUS (HCV) GENOTYPE, TISSUE HCV ANTIGENS, HEPATOCELLULAR EXPRESSION OF HLA-A,B,C, AND INTERCELLULAR ADHESION-1 MOLECULES - CLUES TO PATHOGENESIS OF HEPATOCELLULAR DAMAGE AND RESPONSE TO INTERFERON TREATMENT IN PATIENTS WITH CHRONIC HEPATITIS-C
BALLARDINI, G
GROFF, P
PONTISSO, P
GIOSTRA, F
FRANCESCONI, R
LENZI, M
ZAULI, D
ALBERTI, A
BIANCHI, FB
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (05) : 2067 - 2075
[2] CD8(+) lymphocyte responses to antiretroviral therapy of HIV infection
Carr, A
Emery, S
Kelleher, A
Law, M
Cooper, DA
[J]. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1996, 13 (04): : 320 - 326
[3] GERBER MA, 1995, J HEPATOL, V22, P83
[4] FORMULATION AND APPLICATION OF A NUMERICAL SCORING SYSTEM FOR ASSESSING HISTOLOGICAL ACTIVITY IN ASYMPTOMATIC CHRONIC ACTIVE HEPATITIS
KNODELL, RG
ISHAK, KG
BLACK, WC
CHEN, TS
CRAIG, R
KAPLOWITZ, N
KIERNAN, TW
WOLLMAN, J
[J]. HEPATOLOGY, 1981, 1 (05) : 431 - 435
[5] Molecular epidemiology of Bartonella infections in patients with bacillary angiomatosis-peliosis
Koehler, JE
Sanchez, MA
Garrido, CS
Whitfeld, MJ
Chen, FM
Berger, TG
Rodriguez-Barradas, MC
LeBoit, PE
Tappero, JW
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (26) : 1876 - 1883
[6] CHOLESTATIC HEPATITIS LEADING TO HEPATIC-FAILURE IN A PATIENT WITH ORGAN-TRANSMITTED HEPATITIS-C VIRUS-INFECTION
LIM, HL
LAU, GKK
DAVIS, GL
DOLSON, DJ
LAU, JYN
[J]. GASTROENTEROLOGY, 1994, 106 (01) : 248 - 251
[7] Antiretroviral drugs for AIDS
Lipsky, JJ
[J]. LANCET, 1996, 348 (9030) : 800 - 803
[8] RAPIDLY PROGRESSIVE NON-A, NON-B HEPATITIS IN PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUS-INFECTION
MARTIN, P
DIBISCEGLIE, AM
KASSIANIDES, C
LISKERMELMAN, M
HOOFNAGLE, JH
[J]. GASTROENTEROLOGY, 1989, 97 (06) : 1559 - 1561
[9] Nelson DR, 1997, J IMMUNOL, V158, P1473
[10] Retrospective analysis of the impact of HIV infection and alcohol use on chronic hepatitis C in a large cohort of drug users
Pol, S
Lamorthe, B
Thi, NT
Thiers, V
Carnot, F
Zylberberg, H
Berthelot, P
Bréchot, C
Nalpas, B
[J]. JOURNAL OF HEPATOLOGY, 1998, 28 (06) : 945 - 950

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