A flattened face for membranes

被引:8
作者
Carpenter, CL [1 ]
Cantley, LC
机构
[1] Harvard Univ, Sch Med, Dept Med, Cambridge, MA 02138 USA
[2] Harvard Univ, Sch Med, Dept Cell Biol, Cambridge, MA 02138 USA
[3] Beth Israel Med Ctr, Div Signal Transduct, Boston, MA 02215 USA
关键词
D O I
10.1038/2283
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The solution of the crystal structure of a phosphatidylinositol phosphate kinase has shown it to have a tertiary structure much like protein kinases, but with a flattened face that likely allows it to dock onto membranes.
引用
收藏
页码:843 / 845
页数:3
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