Leukoplakia of oral mucosa: Pathogenesis and possible correction with phytoadaptogen

被引：10

作者：

Bocharova, OA ^{[1
]}

Pozharitskaya, MM

Chekalina, TL

Lyzhenkova, MA

Karpova, RV

Mezentseva, MV

Ershov, FI

机构：

[1] Russian Acad Med Sci, NN Blokhin Russian Ctr Canc Res, Moscow 109801, Russia

[2] Moscow State Med Stomatol Univ, Moscow, Russia

[3] Russian Acad Med Sci, NF Gamaleya Epidemiol & Microbiol Inst, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2004年 / 138卷 / 06期

关键词：

oral leukoplakia; adaptogens; adhesion molecules; immunomodulating therapy;

D O I：

10.1007/s10517-005-0132-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 [基础医学];

摘要：

Leukoplakia of the oral mucosa is characterized by impairment of the epithelial differentiation program. The use of complex phytoadaptogen in the treatment of patients with leukoplakia normalized expression of Fas-APO-1 antigen and keratin 17; increased expression of CD54 attested to activation of immune effectors. The clinical effect manifested in involution or shrinkage and loosening of the pathological focus and complete epithelialization of erosive surfaces. The phytopreparation exhibited adaptogenic effects normalizing the immune and IFN status and improving the state of adaptation systems in the body.

引用

页码：578 / 583

页数：6

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