Possible role of matriptase in the diagnosis of ovarian cancer

被引：20

作者：

Johnson, MD ^{[1
]}

Oberst, MD

Lin, CY

Dickson, RB

机构：

[1] Georgetown Univ, Med Ctr, Vincent T Lombardi Canc Res Ctr, Dept Oncol, Washington, DC 20057 USA

[2] NCI, Canc Res Ctr, Cell & Canc Biol Branch, Bethesda, MD 20892 USA

[3] Georgetown Univ, Med Ctr, Dept Oncol, Washington, DC 20057 USA

来源：

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS | 2003年 / 3卷 / 03期

关键词：

diagnosis; HAI-1; matniptase; ovarian cancer; screening;

D O I：

10.1586/14737159.3.3.331

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

There are increasing data that suggest a role for the serine protease matriptase and its inhibitor, hepatocyte growth factor activator inhibitor-1, in the pathogenesis and progression of ovarian cancer. This review will discuss the matriptase/inhibitor system in the context of ovarian cancer and examine the possibility that this system might be a useful therapeutic and/or diagnostic target in this disease.

引用

页码：331 / 338

页数：8

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