What other biologic and mechanical factors might contribute to osteolysis?

被引：28

作者：

Greenfield, Ed M. ^{[1
]}

Bechtold, Joan ^{[2
,3
,4
]}

机构：

[1] Case Western Reserve Univ, Dept Orthopaed, Cleveland, OH 44106 USA

[2] Univ Minnesota, Midwest Orthopaed Res Fdn, Minneapolis, MN USA

[3] Univ Minnesota, Dept Mech Engn, Minneapolis, MN 55455 USA

[4] Univ Minnesota, Dept Orthopaed Surg, Minneapolis, MN 55455 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS | 2008年 / 16卷

关键词：

D O I：

10.5435/00124635-200800001-00012

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

An overwhelming consensus exists that wear particles are the primary driving force in aseptic loosening of orthopaedic implants. Nonetheless, considerable evidence has emerged demonstrating that various other factors can modulate the biologic activity of orthopaedic wear particles. Two of the most studied modulating factors are bacterial endotoxins and implant motion.

引用

页码：S56 / S62

页数：7

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