Evaluation of Surface Characteristics and Hemocompatibility on the Oxygen Plasma-Modified Biomedical Titanium

被引：20

作者：

Chiang, Hsi-Jen ^{[1
,2
]}

Chou, Hsin-Hua ^{[2
,3
]}

Ou, Keng-Liang ^{[4
,5
,6
,7
,8
,9
]}

Sugiatno, Erwan ^{[8
]}

Ruslin, Muhammad ^{[10
]}

Abd Waris, Rahmat ^{[2
,6
]}

Huang, Chiung-Fang ^{[4
,11
]}

Liu, Chung-Ming ^{[12
,13
]}

Peng, Pei-Wen ^{[11
]}

机构：

[1] Taipei Med Univ, Coll Biomed Engn, Grad Inst Biomed Mat & Tissue Engn, Taipei 110, Taiwan

[2] Taipei Med Univ, Coll Oral Med, Sch Dent, Taipei 110, Taiwan

[3] Taipei Med Univ, Dent Dept, Wan Fang Hosp, Taipei 116, Taiwan

[4] Taipei Med Univ Hosp, Dept Dent, Taipei 110, Taiwan

[5] Taipei Med Univ, Shuang Ho Hosp, Dept Dent, New Taipei 235, Taiwan

[6] Hasanuddin Univ, Fac Dent, Dept Prosthodont, Makassar 90245, Indonesia

[7] Hlth Sci Univ Hokkaido, Sch Dent, Tobetsu, Hokkaido 0610293, Japan

[8] Univ Gadjah Mada, Fac Dent, Dept Prosthodont, Yogyakarta 55281, Indonesia

[9] 3D Global Biotech Inc, New Taipei 221, Taiwan

[10] Hasanuddin Univ, Fac Dent, Dept Oral & Maxillofacial Surg, Makassar 90245, Indonesia

[11] Taipei Med Univ, Sch Dent Technol, Taipei 110, Taiwan

[12] China Med Univ, Coll Med, Sch Dent, Taichung 404, Taiwan

[13] China Med Univ Hosp, Biomed Technol R&D Ctr, Taichung 404, Taiwan

来源：

METALS | 2018年 / 8卷 / 07期

关键词：

oxygen plasma treatment; titanium dioxide; wettability; hemocompatibility; IMMERSION ION-IMPLANTATION; ANTIBACTERIAL MECHANISMS; PLATELET INTERACTIONS; BLOOD; BIOCOMPATIBILITY; MICROSTRUCTURE; TOPOGRAPHY; DEPOSITION; OXIDATION; LAYER;

D O I：

10.3390/met8070513

中图分类号：

T [工业技术];

学科分类号：

120111 [工业工程];

摘要：

Oxygen plasma with different treatment powers and durations was utilized to modify the biomedical pure titanium (Ti) surface in the present study. The superficial, microstructural and biological properties of the plasma-oxidized samples were investigated using the electron microscopy, X-ray photoemission spectroscopy, grazing incidence X-ray diffractometer, contact angle goniometer and blood clotting time assay. During different treatment powers and durations, the island-like nanostructural rutile-TiO2 layer and dimple-like nanostructural rutile-TiO2 layer were generated on the surfaces of the plasma-oxidized samples, respectively. It was also found that the plasma-oxidized sample with a rough oxide layer resulted in the formation of a higher wettability. Moreover, the blood clotting time assay indicated that the plasma-oxidized samples exhibited the adhesion behaviors of red blood cells. As the Ti surface underwent plasma oxidation at 280 W for 30 min, it not only generates a rough nanostructural rutile-TiO2 layer, but also presents an excellent hemocompatibility. Therefore, these findings demonstrate that oxygen plasma modification is a potential approach to promote the hemocompatibility of biomedical pure Ti surface.

引用

页数：10

共 30 条

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