Gene targeting in Physcomitrella patens

被引:148
作者
Schaefer, DG [1 ]
机构
[1] Univ Lausanne, Inst Ecol, Lab Phytogenet Cellulaire, CH-1015 Lausanne, Switzerland
关键词
D O I
10.1016/S1369-5266(00)00150-3
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Gene-targeting efficiency in the land plant Physcomitrella patens (Bryophyta) can only be compared with that observed in Saccharomyces cerevisiae. Sequencing programs and microbiological molecular genetic approaches are now being developed to unravel the precise function of plant genes. Physcomitrella patens, as the new 'green yeast', might well become a major tool for functional genomic studies of multicellular eukaryotes.
引用
收藏
页码:143 / 150
页数:8
相关论文
共 63 条
[1]   Targeted recombination at the Chinese hamster APRT locus using insertion versus replacement vectors [J].
Adair, GM ;
Scheerer, JB ;
Brotherman, A ;
McConville, S ;
Wilson, JH ;
Nairn, RS .
SOMATIC CELL AND MOLECULAR GENETICS, 1998, 24 (02) :91-105
[2]  
[Anonymous], METHOD ENZYMOL
[3]   RELATIONSHIP OF VECTOR INSERT SIZE TO HOMOLOGOUS INTEGRATION DURING TRANSFORMATION OF NEUROSPORA-CRASSA WITH THE CLONED AM (GDH) GENE [J].
ASCH, DK ;
KINSEY, JA .
MOLECULAR AND GENERAL GENETICS, 1990, 221 (01) :37-43
[4]   The bryophyte Physcomitrella patens replicates extrachromosomal transgenic elements [J].
Ashton, NW ;
Champagne, CEM ;
Weiler, T ;
Verkoczy, LK .
NEW PHYTOLOGIST, 2000, 146 (03) :391-402
[5]   Functional genomics in plants [J].
Bouchez, D ;
Höfte, H .
PLANT PHYSIOLOGY, 1998, 118 (03) :725-732
[6]   Molecular genetics of DNA repair in higher plants [J].
Britt, AB .
TRENDS IN PLANT SCIENCE, 1999, 4 (01) :20-25
[7]   INCREASED RATIO OF TARGETED TO RANDOM INTEGRATION AFTER TRANSFECTION OF CHICKEN B-CELL LINES [J].
BUERSTEDDE, JM ;
TAKEDA, S .
CELL, 1991, 67 (01) :179-188
[8]   THE NEW MOUSE GENETICS - ALTERING THE GENOME BY GENE TARGETING [J].
CAPECCHI, MR .
TRENDS IN GENETICS, 1989, 5 (03) :70-76
[9]   ALTERING THE GENOME BY HOMOLOGOUS RECOMBINATION [J].
CAPECCHI, MR .
SCIENCE, 1989, 244 (4910) :1288-1292
[10]   Mosses as model systems [J].
Cove, DJ ;
Knight, CD ;
Lamparter, T .
TRENDS IN PLANT SCIENCE, 1997, 2 (03) :99-105