Community-associated methicillin-resistant Staphylococcus aureus, Minnesota, 2000-2003

被引：59

作者：

Buck, JM ^{[1
]}

Como-Sabetti, K ^{[1
]}

Harriman, KH ^{[1
]}

Danila, RN ^{[1
]}

Boxrud, DJ ^{[1
]}

Glennen, A ^{[1
]}

Lynfield, R ^{[1
]}

机构：

[1] Minnesota Dept Hlth, Acute Dis Invest & Control, Infect Control & Antimicrobial Resistance Unit, Minneapolis, MN 55440 USA

来源：

EMERGING INFECTIOUS DISEASES | 2005年 / 11卷 / 10期

关键词：

D O I：

10.3201/eid1110.050141

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We compared characteristics of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs) and CA-MRSA invasive disease identified in Minnesota from 2000 through 2003. A total of 586 patients with SSTIs and 65 patients with invasive disease were identified. Patients with invasive disease were more likely to be smokers (p = 0.03), and report a history of immunosuppressive therapy (p = 0.03), emphysema (p = 0.011), or injection drug use (p = 0.020) than were SSTI patients. Invasive disease isolates were less likely to be susceptible to ciprofloxacin (p = 0.002) and clindamycin (p = 0.001) and more likely to have healthcare-associated pulsed-field gel electrophoresis subtypes than SSTI isolates (p < 0.001). Patients with invasive disease may have had healthcare exposures that put them at risk of acquiring healthcare-associated MRSA, and which were not exclusion criteria in the CA-MRSA case definition. Continued surveillance of MRSA is needed to better characterize CA-MRSA infections.

引用

页码：1532 / 1538

页数：7

共 34 条

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