Presynaptic imaging techniques

被引：72

作者：

Ryan, TA ^{[1
]}

机构：

[1] Cornell Univ, Weill Med Coll, Dept Biochem, New York, NY 10021 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2001年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0959-4388(00)00247-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Understanding the detailed molecular events that support chemical synaptic transmission requires high-resolution methods that provide quantitative information combined with molecular specificity. In recent years, many new technological approaches, including genetically encoded fluorescent indicators, ultra-thin sectioning, and live-cell imaging have been brought to bear on understanding the cell biology and physiology of presynaptic terminals.

引用

页码：544 / 549

页数：6

共 43 条

[1] Imaging exocytosis and endocytosis [J].

Betz, WJ ;

Mao, F ;

Smith, CB .

CURRENT OPINION IN NEUROBIOLOGY, 1996, 6 (03) :365-371

[2] OPTICAL MONITORING OF TRANSMITTER RELEASE AND SYNAPTIC VESICLE RECYCLING AT THE FROG NEUROMUSCULAR-JUNCTION [J].

BETZ, WJ ;

BEWICK, GS .

JOURNAL OF PHYSIOLOGY-LONDON, 1993, 460 :287-309

[3] OPTICAL ANALYSIS OF SYNAPTIC VESICLE RECYCLING AT THE FROG NEUROMUSCULAR-JUNCTION [J].

BETZ, WJ ;

BEWICK, GS .

SCIENCE, 1992, 255 (5041) :200-203

[4] Single-molecule measurements calibrate green fluorescent protein surface densities on transparent beads for use with 'knock-in' animals and other expression systems [J].

Chiu, CS ;

Kartalov, E ;

Unger, M ;

Quake, S ;

Lester, HA .

JOURNAL OF NEUROSCIENCE METHODS, 2001, 105 (01) :55-63

[5] Monitoring secretory membrane with FM1-43 fluorescence [J].

Cochilla, AJ ;

Angleson, JK ;

Betz, WJ .

ANNUAL REVIEW OF NEUROSCIENCE, 1999, 22 :1-10

[6] Size of vesicle pools, rates of mobilization, and recycling at neuromuscular synapses of a Drosophila mutant, shibire [J].

Delgado, R ;

Maureira, C ;

Oliva, C ;

Kidokoro, Y ;

Labarca, P .

NEURON, 2000, 28 (03) :941-953

[7]

Gustafsson MGL, 1999, J MICROSC-OXFORD, V195, P10, DOI 10.1046/j.1365-2818.1999.00576.x

[8] Spatial sensing in fibroblasts mediated by 3′ phosphoinositides [J].

Haugh, JM ;

Codazzi, F ;

Teruel, M ;

Meyer, T .

JOURNAL OF CELL BIOLOGY, 2000, 151 (06) :1269-1279

[9] Restriction of secretory granule motion near the plasma membrane of chromaffin cells [J].

Johns, LM ;

Levitan, ES ;

Shelden, EA ;

Holz, RW ;

Axelrod, D .

JOURNAL OF CELL BIOLOGY, 2001, 153 (01) :177-190

[10] Imaging synaptic activity in intact brain and slices with FM1-43 in C-elegans, lamprey, and rat [J].

Kay, AR ;

Alfonso, A ;

Alford, S ;

Cline, HT ;

Holgado, AM ;

Sakmann, B ;

Snitsarev, VA ;

Stricker, TP ;

Takahashi, M ;

Wu, LG .

NEURON, 1999, 24 (04) :809-817

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