Statin use and cancer risk in the General Practice Research Database

被引：220

作者：

Kaye, JA ^{[1
]}

Jick, H ^{[1
]}

机构：

[1] Boston Univ, Sch Med, Boston Collaborat Drug Surveillance Program, Lexington, MA 02421 USA

来源：

BRITISH JOURNAL OF CANCER | 2004年 / 90卷 / 03期

关键词：

3-hydroxy-3-methylglutaryl coenzyme A inhibitors; statins; hyperlipidaemia; epidemiology;

D O I：

10.1038/sj.bjc.6601566

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In a matched case-control study using the General Practice Research Database, current statin use was not associated with a significantly altered risk of any of 13 studied cancers. Untreated hyperlipidaemia was associated with slightly increased risks of colon cancer (relative risk 1.8; 95% confidence interval 1.2-2.8), prostate cancer (1.5; 1.1-2.0), and bladder cancer (1.9; 1.2-3.1).

引用

页码：635 / 637

页数：3

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