2-(Aminomethyl)-benzamide-based glycine transporter type-2 inhibitors

被引：13

作者：

Ho, KK

Appell, KC

Baldwin, JJ

Bohnstedt, AC

Dong, GZ

Guo, T

Horlick, R

Islam, KR

Kultgen, SG

Masterson, CM

McDonald, E

McMillan, K

Morphy, JR

Rankovic, Z

Sundaram, H

Webb, M

机构：

[1] Pharmacopeia Inc, Princeton, NJ 08543 USA

[2] Organon Res Labs Ltd, Lead Discovery Unit, Newhouse ML1 5SH, Scotland

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2004年 / 14卷 / 02期

关键词：

D O I：

10.1016/j.bmcl.2003.09.080

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Structure-activity studies on benzamide 1 obtained from library screening led to the discovery of a novel series of potent and selective glycine transporter type-2 inhibitors. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：545 / 548

页数：4

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