Complement and the immune response

被引：76

作者：

Carroll, MC

Fischer, MB

机构：

[1] Department of Pathology, Harvard Med. Sch., Bldg. D-2, R., Boston

来源：

CURRENT OPINION IN IMMUNOLOGY | 1997年 / 9卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(97)80160-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This past year has seen a major advance in our understanding of how the complement system enhances the adaptive immune response. The use of in vivo models has revealed that direct coupling of C3d to antigen is sufficient to dramatically reduce the amount of antigen required for a secondary response. At least one important requirement for th enhancing effect. was determined to be expression of the CD21 (C3d receptor) on B cells.

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页码：64 / 69

页数：6

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