Meiosis: MeiRNA hits the spot

被引:14
作者
Ohno, M [1 ]
Mattaj, IW [1 ]
机构
[1] European Mol Biol Lab, D-69117 Heidelberg, Germany
关键词
D O I
10.1016/S0960-9822(99)80013-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The protein Mei2 performs at least two functions required in fission yeast for the switch from mitotic to meiotic cell cycles. One of these functions also requires meiRNA. It appears that meiRNA targets Mei2 to the nucleus, where it can promote the first meiotic division.
引用
收藏
页码:R66 / R69
页数:4
相关论文
共 12 条
[1]   RAN1+ CONTROLS THE TRANSITION FROM MITOTIC DIVISION TO MEIOSIS IN FISSION YEAST [J].
BEACH, D ;
RODGERS, L ;
GOULD, J .
CURRENT GENETICS, 1985, 10 (04) :297-311
[2]   MPF localization is controlled by nuclear export [J].
Hagting, A ;
Karlsson, C ;
Clute, P ;
Jackman, M ;
Pines, J .
EMBO JOURNAL, 1998, 17 (14) :4127-4138
[3]   A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export [J].
Lee, MS ;
Henry, M ;
Silver, PA .
GENES & DEVELOPMENT, 1996, 10 (10) :1233-1246
[4]   STRUCTURE OF SPLICEOSOMAL SNRNPS AND THEIR ROLE IN PRE-MESSENGER-RNA SPLICING [J].
LUHRMANN, R ;
KASTNER, B ;
BACH, M .
BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1087 (03) :265-292
[5]   Nucleocytoplasmic transport: The soluble phase [J].
Mattaj, IW ;
Englmeier, L .
ANNUAL REVIEW OF BIOCHEMISTRY, 1998, 67 :265-306
[6]   A distinct and parallel pathway for the nuclear import of an mRNA-binding protein [J].
Pemberton, LF ;
Rosenblum, JS ;
Blobel, G .
JOURNAL OF CELL BIOLOGY, 1997, 139 (07) :1645-1653
[7]   SHUTTLING OF PRE-MESSENGER-RNA BINDING-PROTEINS BETWEEN NUCLEUS AND CYTOPLASM [J].
PINOLROMA, S ;
DREYFUSS, G .
NATURE, 1992, 355 (6362) :730-732
[8]   Cytoplasmic retention and nuclear import of 5S ribosomal RNA containing RNPs [J].
Rudt, F ;
Pieler, T .
EMBO JOURNAL, 1996, 15 (06) :1383-1391
[9]   Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Np13p [J].
Senger, B ;
Simos, G ;
Bischoff, FR ;
Podtelejnikov, A ;
Mann, M ;
Hurt, E .
EMBO JOURNAL, 1998, 17 (08) :2196-2207
[10]   S-POMBE-MEI2(+) ENCODES AN RNA-BINDING PROTEIN ESSENTIAL FOR PREMEIOTIC DNA-SYNTHESIS AND MEIOSIS-I, WHICH COOPERATES WITH A NOVEL RNA SPECIES MEIRNA [J].
WATANABE, Y ;
YAMAMOTO, M .
CELL, 1994, 78 (03) :487-498