Controlled spacing of cationic gold nanoparticles by nanocrown RNA

被引:54
作者
Koyfman, AY
Braun, G
Magonov, S
Chworos, A
Reich, NO
Jaeger, L [1 ]
机构
[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Biomol Sci & Engn Program, Santa Barbara, CA 93106 USA
[2] Veeco Instruments, Goleta, CA 93117 USA
关键词
D O I
10.1021/ja051144m
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Using atomic force microscopy, we describe the linear arrangement of cationic gold nanoparticles directed by programmable self-assembling RNA ladders and demonstrate that the regular spacing of nanoparticles is controlled by the RNA architecture acting as nanocrown scaffoldings. Thus, precise positioning of molecular components can be accomplished with RNA not only through electrostatic but also via size and shape recognitions. Copyright © 2005 American Chemical Society.
引用
收藏
页码:11886 / 11887
页数:2
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