1-alkylpyrazoles and 1-alkyl-5-chloropyrazoles from halovinyl ketones and 1,1-dialkylhydrazines

被引：11

作者：

Bozhenkov, G. N. ^{[1
]}

Savosik, V. A. ^{[1
]}

Klyba, L. V. ^{[1
]}

Zhanchipova, E. R. ^{[1
]}

Mirskova, A. N. ^{[1
]}

Levkovskaya, G. G. ^{[1
]}

机构：

[1] Russian Acad Sci, Favorskii Irkutsk Inst Chem, Siberian Div, Irkutsk 664033, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 44卷 / 08期

基金：

俄罗斯基础研究基金会;

关键词：

Pyrazole; Hydrazone; Halogen Atom; Vinyl Ketone; Anhydrous Diethyl Ether;

D O I：

10.1134/S1070428008080150

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regioselective heterocyclization of alkyl 2-chloro- and 2,2-dichlorovinyl ketones with 1,1-dialkylhydrazines to 1,3-dialkyl-1H-pyrazoles and 1,3-dialkyl-5-chloro-1H-pyrizoles involves intermediate formation of the corresponding dialkylhydrazones. Fragmentation pattern of chlorine-containing pyrazoles, 3-chloromethyl-1-methyl-1H-pyrazole and 5-chloro-1-methyl-3-propyl-1H-pyrazole, depends on the position of the halogen atom.

引用

页码：1194 / 1199

页数：6

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