Highly efficient ligands for palladium-catalyzed asymmetric alkylation of ketone enolates

被引：145

作者：

You, SL ^{[1
]}

Hou, XL ^{[1
]}

Dai, LX ^{[1
]}

Zhu, XZ ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Organomet Chem Lab, Shanghai 200032, Peoples R China

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 02期

关键词：

D O I：

10.1021/ol0067033

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Ferrocene modified chiral pocket ligands have been studied in the palladium catalyzed asymmetric alkylation of simple ketone enolates, in which (R,R,Sp,Sp)-1 containing two pairs of matched chiralities, central chirality and planar chirality, behaved very efficiently in this reaction and up to 95% ee value was achieved.

引用

页码：149 / 151

页数：3

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