Glycine transporters not only take out the garbage, they recycle

被引：12

作者：

Brasnjo, G ^{[1
]}

Otis, TS ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Sch Med, Dept Neurobiol, Los Angeles, CA 90095 USA

来源：

NEURON | 2003年 / 40卷 / 04期

关键词：

D O I：

10.1016/S0896-6273(03)00725-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Two articles in the current issue of Neuron examine the consequences of deleting the two genes that encode glycine transporters. Interestingly, loss of glial transporters enhances while loss of presynaptic neuronal transporters reduces glycinergic transmission. These two opposing phenotypes resemble distinct human diseases characterized by dysfunction in glycinergic signaling.

引用

页码：667 / 669

页数：3

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