Presence of human herpesvirus 6 variants A and B in saliva and peripheral blood mononuclear cells of healthy adults

被引：37

作者：

Aberle, SW

Mandi, CW

Kunz, C

PopowKraupp, T

机构：

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1996年 / 34卷 / 12期

关键词：

D O I：

10.1128/JCM.34.12.3223-3225.1996

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Saliva and peripheral blood mononuclear cells (PBMCs) from 44 healthy young adults were tested for human herpesvirus 6 variants A and B (HHV-6A and -6B) DNA by a sensitive nested PCR. HHV-6B infection was ascertained in 98% of the subjects, and 95% were found to excrete variant B in their saliva. HHV-6A was found in the PBMCs of 16%, but was not detected in saliva samples.

引用

收藏

页码：3223 / 3225

页数：3

相关论文

共 24 条

[1] GENOMIC POLYMORPHISM, GROWTH-PROPERTIES, AND IMMUNOLOGICAL VARIATIONS IN HUMAN HERPESVIRUS-6 ISOLATES [J].

ABLASHI, DV ;

BALACHANDRAN, N ;

JOSEPHS, SF ;

HUNG, CL ;

KRUEGER, GRF ;

KRAMARSKY, B ;

SALAHUDDIN, SZ ;

GALLO, RC .

VIROLOGY, 1991, 184 (02) :545-552

[2] Coinfection with human herpesvirus 6 variants A and B in lung tissue [J].

Cone, RW ;

Huang, MLW ;

Hackman, RC ;

Corey, L .

JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (04) :877-881

[3] HUMAN HERPESVIRUS-6 DNA IN PERIPHERAL-BLOOD CELLS AND SALIVA FROM IMMUNOCOMPETENT INDIVIDUALS [J].

CONE, RW ;

HUANG, MLW ;

ASHLEY, R ;

COREY, L .

JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (05) :1262-1267

[4] HIGH PREVALENCE OF HHV-6 DNA IN PERIPHERAL-BLOOD MONONUCLEAR-CELLS OF HEALTHY-INDIVIDUALS DETECTED BY NESTED-PCR [J].

CUENDE, JI ;

RUIZ, J ;

CIVEIRA, MP ;

PRIETO, J .

JOURNAL OF MEDICAL VIROLOGY, 1994, 43 (02) :115-118

[5] HUMAN HERPESVIRUS-6 (HHV-6) VARIANT-B ACCOUNTS FOR THE MAJORITY OF SYMPTOMATIC PRIMARY HHV-6 INFECTIONS IN A POPULATION OF UNITED-STATES INFANTS [J].

DEWHURST, S ;

MCINTYRE, K ;

SCHNABEL, K ;

HALL, CB .

JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (02) :416-418

[6] HUMAN HERPESVIRUS-6 AND HUMAN HERPESVIRUS-7 IN CHRONIC FATIGUE SYNDROME [J].

DILUCA, D ;

ZORZENON, M ;

MIRANDOLA, P ;

COLLE, R ;

BOTTA, GA ;

CASSAI, E .

JOURNAL OF CLINICAL MICROBIOLOGY, 1995, 33 (06) :1660-1661

[7] HUMAN HERPESVIRUSES 6 AND 7 IN SALIVARY-GLANDS AND SHEDDING IN SALIVA OF HEALTHY AND HUMAN-IMMUNODEFICIENCY-VIRUS POSITIVE INDIVIDUALS [J].

DILUCA, D ;

MIRANDOLA, P ;

RAVAIOLI, T ;

DOLCETTI, R ;

FRIGATTI, A ;

BOVENZI, P ;

SIGHINOLFI, L ;

MONINI, P ;

CASSAI, E .

JOURNAL OF MEDICAL VIROLOGY, 1995, 45 (04) :462-468

[8] HUMAN HERPESVIRUS-6 - A SURVEY OF PRESENCE AND VARIANT DISTRIBUTION IN NORMAL PERIPHERAL LYMPHOCYTES AND LYMPHOPROLIFERATIVE DISORDERS [J].

DILUCA, D ;

DOLCETTI, R ;

MIRANDOLA, P ;

DE RE, V ;

SECCHIERO, P ;

CARBONE, A ;

BOIOCCHI, M ;

CASSAI, E .

JOURNAL OF INFECTIOUS DISEASES, 1994, 170 (01) :211-215

[9] HUMAN HERPESVIRUS-6 DNA IN BLOOD-CELLS OF HUMAN IMMUNODEFICIENCY VIRUS-INFECTED MEN - CORRELATION OF HIGH-LEVELS WITH HIGH CD4 CELL COUNTS [J].

FAIRFAX, MR ;

SCHACKER, T ;

CONE, RW ;

COLLIER, AC ;

COREY, L .

JOURNAL OF INFECTIOUS DISEASES, 1994, 169 (06) :1342-1345

[10] HUMAN HERPESVIRUS-6 IN SALIVARY-GLANDS [J].

FOX, JD ;

BRIGGS, M ;

WARD, PA ;

TEDDER, RS .

LANCET, 1990, 336 (8715) :590-593