Cell biology - Earthworms and lipid couriers

被引:20
作者
Munro, S [1 ]
机构
[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
关键词
D O I
10.1038/426775a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Lipids can hop between cellular compartments without using the transport vesicles that carry proteins. A key molecule involved in conveying the lipid ceramide has at last been uncovered.
引用
收藏
页码:775 / 776
页数:2
相关论文
共 13 条
  • [1] Ceramide:: does it matter for T cells?
    Adam, D
    Heinrich, M
    Kabelitz, D
    Schütze, S
    [J]. TRENDS IN IMMUNOLOGY, 2002, 23 (01) : 1 - 4
  • [2] COLLINS RN, 1992, J BIOL CHEM, V267, P24906
  • [3] Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells
    Fukasawa, M
    Nishijima, M
    Hanada, K
    [J]. JOURNAL OF CELL BIOLOGY, 1999, 144 (04) : 673 - 685
  • [4] Molecular machinery for non-vesicular trafficking of ceramide
    Hanada, K
    Kumagai, K
    Yasuda, S
    Miura, Y
    Kawano, M
    Fukasawa, M
    Nishijima, M
    [J]. NATURE, 2003, 426 (6968) : 803 - 809
  • [5] Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated
    Kok, JW
    Babia, T
    Klappe, K
    Egea, G
    Hoekstra, D
    [J]. BIOCHEMICAL JOURNAL, 1998, 333 : 779 - 786
  • [6] Golgi structure in three dimensions: Functional insights from the normal rat kidney cell
    Ladinsky, MS
    Mastronarde, DN
    McIntosh, JR
    Howell, KE
    Staehelin, LA
    [J]. JOURNAL OF CELL BIOLOGY, 1999, 144 (06) : 1135 - 1149
  • [7] The OSBP-related proteins: a novel protein family involved in vesicle transport, cellular lipid metabolism, and cell signalling
    Lehto, M
    Olkkonen, VM
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2003, 1631 (01): : 1 - 11
  • [8] Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components
    Levine, TP
    Munro, S
    [J]. CURRENT BIOLOGY, 2002, 12 (09) : 695 - 704
  • [9] A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP
    Loewen, CJR
    Roy, A
    Levine, TP
    [J]. EMBO JOURNAL, 2003, 22 (09) : 2025 - 2035
  • [10] A NOVEL FLUORESCENT CERAMIDE ANALOG FOR STUDYING MEMBRANE TRAFFIC IN ANIMAL-CELLS - ACCUMULATION AT THE GOLGI-APPARATUS RESULTS IN ALTERED SPECTRAL PROPERTIES OF THE SPHINGOLIPID PRECURSOR
    PAGANO, RE
    MARTIN, OC
    KANG, HC
    HAUGLAND, RP
    [J]. JOURNAL OF CELL BIOLOGY, 1991, 113 (06) : 1267 - 1279