Parametric imaging for myocardial contrast echocardiography: Pixel-by-pixel incorporation of information from both spatial and temporal domains

被引：5

作者：

Sklenar, J ^{[1
]}

Jayaweera, AR ^{[1
]}

Linka, AZ ^{[1
]}

Kaul, S ^{[1
]}

机构：

[1] Univ Virginia, Charlottesville, VA 22903 USA

来源：

COMPUTERS IN CARDIOLOGY 1998, VOL 25 | 1998年 / 25卷

关键词：

D O I：

10.1109/CIC.1998.731902

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Ultrasound can be used to destroy microbubbles during their continuous infusion, and their rate of myocardial replenishment can be measured by progressively increasing the pulsing interval (PI). We have developed an algorithm that incorporates information from both the spatial and temporal domains. The pre-contrast images and contrast-enhanced images are selected from images acquired for each pulsing interval images are aligned, averaged, and subtracted. Video-intensity (VI) is measured in each pixel, and the resulting PI versus VI plot for each pixel is fitted to an exponential function: y=A(1-e(-beta t)), where y is VI at PI t, A represents microvascular cross-sectional area, beta represents the mean microbubble velocity, and A.beta represents myocardial blood flow. These values are represented in color as separate parametric images. This new method offers a simple and easy means for assessing the spatial and temporal characteristics of myocardial perfusion during MCE.

引用

页码：461 / 464

页数：4