Zinc Barbier reaction of propargyl halides in water

被引：48

作者：

Bieber, LW ^{[1
]}

da Silva, MF ^{[1
]}

da Costa, RC ^{[1
]}

Silva, LOS ^{[1
]}

机构：

[1] Univ Fed Pernambuco, Dept Quim Fundamental, BR-50670901 Recife, PE, Brazil

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(98)00641-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of propargyl halides and carbonyl compounds with zinc powder proceeds in concentrated aqueous salt solutions affording with high selectivity homopropargylic alcohols. Preparatively useful yields are obtained with aromatic and aliphatic aldehydes. Ketones and 2-hydroxybenzaldehydes react partially. A surface process of two SET is discussed. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：3655 / 3658

页数：4

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