The T-SCAN™ technology:: electrical impedance as a diagnostic tool for breast cancer detection

被引:99
作者
Assenheimer, M [1 ]
Laver-Moskovitz, O [1 ]
Malonek, D [1 ]
Manor, D [1 ]
Nahaliel, U [1 ]
Nitzan, R [1 ]
Saad, A [1 ]
机构
[1] TransScan Med Ltd, IL-10550 Migdal Ha Emek, Israel
关键词
electrical impedance; breast cancer; tissue differentiation;
D O I
10.1088/0967-3334/22/1/301
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
In this paper we present the T-SCAN(TM) technology and its use as a diagnostic tool for breast cancer detection. We show, using theoretical models with simplified geometries, that displaying planar two-dimensional maps of the currents detected at the breast's surface relate to the electric field distribution within the breast. This distribution is a manifestation of the bulk spatial inhomogeneities in the complex dielectric constant that represent the various tissue types. These differences may be used to discriminate between various pathological states. We furthermore illustrate a useful classifier, based on admittance data measured up to 2 kHz, and we argue that low frequency impedance measurements can be used successfully in breast cancer diagnosis.
引用
收藏
页码:1 / 8
页数:8
相关论文
共 12 条
[1]  
*ACS, 1997, SURV RES
[2]  
[Anonymous], 1998, CLASSICAL ELECTRODYN
[3]   APPLIED POTENTIAL TOMOGRAPHY [J].
BARBER, DC ;
BROWN, BH .
JOURNAL OF PHYSICS E-SCIENTIFIC INSTRUMENTS, 1984, 17 (09) :723-733
[4]   Relation between tissue structure and imposed electrical current flow in cervical neoplasia [J].
Brown, BH ;
Tidy, JA ;
Boston, K ;
Blackett, AD ;
Smallwood, RH ;
Sharp, F .
LANCET, 2000, 355 (9207) :892-895
[5]   The impedivity of freshly excised human breast tissue [J].
Jossinet, J .
PHYSIOLOGICAL MEASUREMENT, 1998, 19 (01) :61-75
[6]   Variability of impedivity in normal and pathological breast tissue [J].
Jossinet, J .
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 1996, 34 (05) :346-350
[7]   MEASUREMENT OF THE ELECTRICAL BIOIMPEDANCE OF BREAST-TUMORS [J].
MORIMOTO, T ;
KINOUCHI, Y ;
IRITANI, T ;
KIMURA, S ;
KONISHI, Y ;
MITSUYAMA, N ;
KOMAKI, K ;
MONDEN, Y .
EUROPEAN SURGICAL RESEARCH, 1990, 22 (02) :86-92
[8]  
PIPERNO G, 1990, Frontiers of Medical and Biological Engineering, V2, P111
[9]   SKIN IMPEDANCE FROM 1 HZ TO 1 MHZ [J].
ROSELL, J ;
COLOMINAS, J ;
RIU, P ;
PALLASARENY, R ;
WEBSTER, JG .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1988, 35 (08) :649-651
[10]   INVIVO DIELECTRIC SPECTROMETER [J].
SINGH, B ;
SMITH, CW ;
HUGHES, R .
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 1979, 17 (01) :45-60