Cerebral networks linked to the event-related potential P300

被引：35

作者：

Horn, H

Syed, N

Lanfermann, H

Maurer, K

Dierks, T

机构：

[1] Univ Bern, Hosp Clin Psychiat, Dept Psychiat Neurophysiol, Bern, Switzerland

[2] Univ Frankfurt, Clin Neurophysiol Lab, Dept Psychiat 1, Frankfurt, Germany

[3] Univ Frankfurt, Dept Neuroradiol, D-6000 Frankfurt, Germany

来源：

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE | 2003年 / 253卷 / 03期

关键词：

P3; generators; event related potentials; oddball paradigm; working memory;

D O I：

10.1007/s00406-003-0419-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

P300 is an event-related potential that is elicited by an oddball paradigm. In several neuropsychiatric diseases, differences in latencies and amplitude compared to healthy subjects have been reported. Because of its clinical significance, several investigations have tried to elucidate the intracranial origins of the P300 component. In the present study we could demonstrate a network of P300 generators. Investigated were 15 healthy subjects with an acoustical oddball paradigm within a fMRI block design, which enabled us to exclude attention or acoustical processing effects. The inferior and middle frontal, superior temporal, lower parietal cortex, the insula and the anterior cingulum were significantly activated symmetrical in both hemispheres.

引用

页码：154 / 159

页数：6

共 39 条

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