The physics of molecular motors

被引:248
作者
Bustamante, C [1 ]
Keller, D
Oster, G
机构
[1] Univ Calif Berkeley, Howard Hughes Med Inst, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA
[3] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
[4] Univ Calif Berkeley, ESPM, Berkeley, CA 94720 USA
[5] Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA
关键词
D O I
10.1021/ar0001719
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Molecular motors convert chemical energy into mechanical force and movement. Operating at energies just above those of the thermal bath, these motors experience large fluctuations, and their physical description must be necessarily stochastic. Here, motor operation is described as a biased diffusion on a potential energy surface defined by the interactions of the motor with its track and its fuel. These ideas are illustrated with a model of the rotary movement of the F-o motor.
引用
收藏
页码:412 / 420
页数:9
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