Incorporation of vancomycin-supplemented bone allografts -: Radiographical, histopathological and immunohistochemical study in pigs

被引：37

作者：

Buttaro, MA

Della Valle, AMG

Piñeiro, L

Mocetti, E

Morandi, AA

Piccaluga, F

机构：

[1] Hosp Italiano Buenos Aires, Inst Orthopaed Carlos E Ottolenghi, Buenos Aires, DF, Argentina

[2] Hosp Italiano Buenos Aires, Dept Pathol, Buenos Aires, DF, Argentina

来源：

ACTA ORTHOPAEDICA SCANDINAVICA | 2003年 / 74卷 / 05期

关键词：

D O I：

10.1080/00016470310017884

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We compared the incorporation of bone allografts with or without vancomycin in tibial defects of 18 pigs. High-quality radiographs, histological examination, immunological expression of metalloproteinase-13 (MMP-13) and transforming growth factor-beta 2 (TGFB(2)) indicated that there was no significant difference in bone allograft incorporation between up to 220 times the MIC (minimum inhibitory concentration) in bone allografts with 1 g of vancomycin in each 300 g of allograft or without this supplement.

引用

页码：505 / 513

页数：9

共 27 条

[1]

DEMONSTRATION OF TGF-BETA-1 MESSENGER-RNA BY INSITU HYBRIDIZATION IN NORMAL HUMAN FRACTURE-HEALING [J].