Biosynthesis of the isoprene units of chamomile sesquiterpenes

被引：110

作者：

Adam, KP ^{[1
]}

Zapp, J ^{[1
]}

机构：

[1] Univ Saarland, FR Pharmakognosie & Analyt Phytochem 12 3, D-66041 Saarbrucken, Germany

来源：

PHYTOCHEMISTRY | 1998年 / 48卷 / 06期

关键词：

D O I：

10.1016/S0031-9422(97)00992-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chamomile sesquiterpenes were labelled with C-13 by injection of an [1-C-13]glucose solution into the anthodia of the plant. The sesquiterpenes bisabololoxide A and chamazulene were isolated from the hydrodistillate of the labelled flowers. Analysis of the labelling patterns and absolute C-13 abundances using quantitative C-13 NMR spectroscopy showed that two of the isoprene building blocks were predominantly formed via the new triose/pyruvate pathway, whereas the third unit was of mixed origin, being derived from both the mevalonic acid pathway and the triose/pyruvate pathway. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：953 / 959

页数：7

共 16 条

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