Calcineurin anchoring and cell signaling

被引：27

作者：

Dodge, KL ^{[1
]}

Scott, JD ^{[1
]}

机构：

[1] Oregon Hlth & Sci Univ, Howard Hughes Med Inst, Vollum Inst, Portland, OR 97201 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2003年 / 311卷 / 04期

关键词：

D O I：

10.1016/j.bbrc.2003.09.040

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The targeting of phosphatase PP2B or calcineurin toward certain substrates synchronizes a variety of physiological processes. This review emphasizes how the targeting of calcineurin through interaction with various anchoring proteins facilitates phosphatase regulation of T-cell activation, neuronal excitability and cardiac hypertrophy. (C) 2003 Elsevier Inc. All rights reserved.

引用

页码：1111 / 1115

页数：5

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