Isolation and characterization of a hemin-binding cell envelope protein from Porphyromonas gingivalis

被引：22

作者：

Kim, SJ ^{[1
]}

Chu, L ^{[1
]}

Holt, SC ^{[1
]}

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT MICROBIOL,SAN ANTONIO,TX 78284

来源：

MICROBIAL PATHOGENESIS | 1996年 / 21卷 / 01期

关键词：

hemin; Porphyromonas gingivalis; TMBZ; outer membranes;

D O I：

10.1006/mpat.1996.0043

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 30 kDa (heated 24 kDa) hemin-binding protein whose expression is both hemin and iron regulated was identified and purified in Porphyromonas gingivalis 381. A strong hemin-binding function was found by LDS-PAGE and TMBZ staining when cells were grown under hemin (iron)-limited conditions. N-terminal amino acid sequence analysis of CNBr-digested 24 kDa hemin binding protein revealed that this protein belongs to a new, so far undescribed hemin-binding class of proteins. (C) 1996 Academic Press Limited

引用

页码：65 / 70

页数：6

共 20 条

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