Efficient synthesis of β,γ-alkynyl α-amino acid derivatives by Ag(I)-catalyzed alkynylation of α-imino esters

被引：72

作者：

Ji, JX

Au-Yeung, TL

Wu, J

Yip, CW

Chan, ASC ^{[1
]}

机构：

[1] Hong Kong Polytech Univ, Inst Mol Technol Drug Discovery, Open Lab Chirotechnol, Hong Kong, Hong Kong, Peoples R China

[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2004年 / 346卷 / 01期

关键词：

alkynes; alpha-amino acids; alpha-imino ester; catalytic synthesis; silver(I) salt;

D O I：

10.1002/adsc.200303148

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The first catalytic synthesis of beta,gamma-alkynyl alpha-amino acid derivatives was achieved by direct addition of terminal alkynes to alpha-imino esters in the presence of an Ag(I) salt under mild reaction conditions.

引用

页码：42 / 44

页数：3

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