Self-poisoning with Colchicum autumnale L. flowers

被引:19
作者
Danel, VC
Wiart, JFD
Hardy, GA
Vincent, FH
Houdret, NMP
机构
[1] CHU Grenoble, Dept Pluridisciplinaire Med, Unite Toxicol Clin, F-38043 Grenoble 9, France
[2] CHU Lille, Hop Calmette, F-59037 Lille, France
来源
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY | 2001年 / 39卷 / 04期
关键词
D O I
10.1081/CLT-100105163
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
Report: A 44-year-old man ingested about 40 flowers of Colchicum autumnale L. The patient presented with nausea, vomiting, and abdominal pain 2 hours after ingestion and had diarrhea 14 hours after ingestion. Hematological values remained within normal range. Treatment was mainly supportive. The outcome was favorable. The intoxication was confirmed by. high-performance liquid chromatography-mass spectrometry. Maximal colchicine levels were 4.34 ng/mL at 13 hours in plasma and 5.43 ng/mL at 16 hours in erythrocytes. Conclusion: We report one of the few symptomatic cases of Colchicum autumnale L. poisoning confirmed by toxicological analysis.
引用
收藏
页码:409 / 411
页数:3
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