Cooling garment treatment in MS: Clinical improvement and decrease in leukocyte NO production

被引：54

作者：

Beenakker, EAC

Oparina, TI

Hartgring, A

Teelken, A

Arutjunyan, AV

De Keyser, J

机构：

[1] Acad Ziekenhuis Groningen, Dept Neurol, NL-9700 RB Groningen, Netherlands

[2] Russian Acad Med Sci, Lab Perinatal Biochem, St Petersburg, Russia

[3] Russian Acad Med Sci, DO Ott Res Inst Obstet & Gynecol, St Petersburg, Russia

来源：

NEUROLOGY | 2001年 / 57卷 / 05期

关键词：

D O I：

10.1212/WNL.57.5.892

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Ten heat-sensitive patients with MS were randomly allocated in a cross-over study to wear a cooling garment for 60 minutes at 7 degreesC (active cooling) and 26 degreesC (sham cooling). In contrast to sham cooling, active cooling improved fatigue and postural stability with eyes closed and muscle strength. There was no decrease in tympanic temperature, but active cooling was associated with a 41% decrease in mean leukocyte nitric oxide (NO) production (p = 0.004). This effect on NO could be relevant because it blocks conduction in demyelinated axons.

引用

页码：892 / 894

页数：3

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