Molecular determinants of human immunodeficiency virus type I phenotype variability

被引：6

作者：

Fouchier, RAM

Schuitemaker, H

机构：

[1] NETHERLANDS RED CROSS,BLOOD TRANSFUS SERV,CENT LAB,DEPT CLIN VIROIMMUNOL,1066 CX AMSTERDAM,NETHERLANDS

[2] UNIV AMSTERDAM,EXPTL & CLIN IMMUNOL LAB,AMSTERDAM,NETHERLANDS

来源：

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 1996年 / 26卷 / 03期

关键词：

biological phenotype; gp120; HIV-1; pathogenesis replication rate; syncytium inducing capacity;

D O I：

10.1046/j.1365-2362.1996.130266.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The clinical course of HIV-1-infected individuals can be highly variable. Progression to AIDS can occur within 1 year after infection but symptom-free infection for more than 15 years has also been reported. This variation can either be determined by host factors, the biological variability of the virus or both. Here the molecular determinants and clinical relevance of HIV-1 biological phenotype variability are reviewed.

引用

收藏

页码：175 / 185

页数：11

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