Lignans as anti-tumor-promoter from the seeds of Hernandia ovigera

被引：20

作者：

Ito, C

Itoigawa, M ^{[1
]}

Ogata, M

Mou, XY

Tokuda, H

Nishino, H

Furukawa, H

机构：

[1] Tokai Gakuen Univ, Aichi 4700207, Japan

[2] Meijo Univ, Fac Pharm, Tempaku Ku, Nagoya, Aichi 468, Japan

[3] Kyoto Prefectural Univ Med, Dept Biochem, Kamigyo Ku, Kyoto 602, Japan

来源：

PLANTA MEDICA | 2001年 / 67卷 / 02期

关键词：

D O I：

10.1055/s-2001-11501

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Seven lignans (2-8) isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) were tested for their inhibitory effects on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoylphorbol 13-acetate in Raji cells. Using a primary screening test, all the lignans showed inhibitory activity with IC50 470-590 mol ratio/32 pmol TPA. The data demonstrated that these lignans might be valuable anti-tumor-promoters.

引用

页码：166 / 168

页数：3

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