Lp(a) levels in Greek patients with heterozygous familial hypercholesterolemia

被引：8

作者：

Elisaf, M

Bairaktari, H

Siamopoulos, KC

机构：

[1] UNIV IOANNINA,SCH MED,DEPT INTERNAL MED,GR-45110 IOANNINA,GREECE

[2] UNIV IOANNINA,SCH MED,BIOCHEM LAB,GR-45110 IOANNINA,GREECE

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 1996年 / 53卷 / 03期

关键词：

familial hypercholesterolemia; Lp(a); lipids; coronary heart disease;

D O I：

10.1016/0167-5273(95)02542-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We undertook the present study to evaluate the lipid profile in 82 (51 male, 31 female) Greek individuals with heterozygous familial hypercholesterolemia (FH), aged 13-61 years from 22 families. FH heterozygotes had significantly elevated serum Lp(a) levels in comparison with 82 normal controls. Serum Lp(a) levels were also increased in FH probands compared to their controls. Additionally, serum Lp(a) concentration was elevated in the FH heterozygotes compared to their unaffected first degree relatives.

引用

页码：314 / 316

页数：3

共 5 条

[1] OVEREXPRESSION OF HUMAN LOW-DENSITY-LIPOPROTEIN RECEPTORS LEADS TO ACCELERATED CATABOLISM OF LP(A) LIPOPROTEIN IN TRANSGENIC MICE [J].