Cells in sol-gels I: A cytocompatible route for the production of macroporous silica gels

被引：50

作者：

Conroy, JFT ^{[1
]}

Power, ME ^{[1
]}

Martin, J ^{[1
]}

Earp, B ^{[1
]}

Hosticka, B ^{[1
]}

Daitch, CE ^{[1
]}

Norris, PM ^{[1
]}

机构：

[1] Univ Virginia, Dept Mech & Aerosp Engn, Charlottesville, VA 22903 USA

来源：

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY | 2000年 / 18卷 / 03期

关键词：

bacteria; immobilization; sol-gel production; macroporous;

D O I：

10.1023/A:1008704208324

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A novel, high hydrolysis ratio sol-gel route for the biocompatible production of macroporous silica gels is presented. This route exploits the two step nature of the gelation reaction to remove undesired alcohol by-products from an acidic aqueous sol prior to gelation. These alcohol-free sols will gel when the pH is raised to the physiologic range in a two-step, acid/base catalyzed process. Furthermore, monolithic macroporous samples can be produced in a controlled manner by introducing water-soluble organic polymers into the sol.

引用

页码：269 / 283

页数：15

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