Crohn's Disease Susceptibility Gene Interactions, a NOD to the Newcomer ATG16L1

被引:26
作者
Cadwell, Ken [1 ]
机构
[1] NYU, Skirball Inst Biomol Med, Dept Microbiol, Sch Med, New York, NY 10016 USA
关键词
GENOME-WIDE ASSOCIATION; AUTOPHAGY; MUTATION; RECOGNITION; IMMUNITY;
D O I
10.1053/j.gastro.2010.09.023
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:1448 / 1450
页数:3
相关论文
共 25 条
[1]
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease [J].
Barrett, Jeffrey C. ;
Hansoul, Sarah ;
Nicolae, Dan L. ;
Cho, Judy H. ;
Duerr, Richard H. ;
Rioux, John D. ;
Brant, Steven R. ;
Silverberg, Mark S. ;
Taylor, Kent D. ;
Barmada, M. Michael ;
Bitton, Alain ;
Dassopoulos, Themistocles ;
Datta, Lisa Wu ;
Green, Todd ;
Griffiths, Anne M. ;
Kistner, Emily O. ;
Murtha, Michael T. ;
Regueiro, Miguel D. ;
Rotter, Jerome I. ;
Schumm, L. Philip ;
Steinhart, A. Hillary ;
Targan, Stephan R. ;
Xavier, Ramnik J. ;
Libioulle, Cecile ;
Sandor, Cynthia ;
Lathrop, Mark ;
Belaiche, Jacques ;
Dewit, Olivier ;
Gut, Ivo ;
Heath, Simon ;
Laukens, Debby ;
Mni, Myriam ;
Rutgeerts, Paul ;
Van Gossum, Andre ;
Zelenika, Diana ;
Franchimont, Denis ;
Hugot, Jean-Pierre ;
de Vos, Martine ;
Vermeire, Severine ;
Louis, Edouard ;
Cardon, Lon R. ;
Anderson, Carl A. ;
Drummond, Hazel ;
Nimmo, Elaine ;
Ahmad, Tariq ;
Prescott, Natalie J. ;
Onnie, Clive M. ;
Fisher, Sheila A. ;
Marchini, Jonathan ;
Ghori, Jilur .
NATURE GENETICS, 2008, 40 (08) :955-962
[2]
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells [J].
Cadwell, Ken ;
Liu, John Y. ;
Brown, Sarah L. ;
Miyoshi, Hiroyuki ;
Loh, Joy ;
Lennerz, Jochen K. ;
Kishi, Chieko ;
Kc, Wumesh ;
Carrero, Javier A. ;
Hunt, Steven ;
Stone, Christian D. ;
Brunt, Elizabeth M. ;
Xavier, Ramnik J. ;
Sleckman, Barry P. ;
Li, Ellen ;
Mizushima, Noboru ;
Stappenbeck, Thaddeus S. ;
Virgin, Herbert W. .
NATURE, 2008, 456 (7219) :259-U62
[3]
Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine [J].
Cadwell, Ken ;
Patel, Khushbu K. ;
Maloney, Nicole S. ;
Liu, Ta-Chiang ;
Ng, Aylwin C. Y. ;
Storer, Chad E. ;
Head, Richard D. ;
Xavier, Ramnik ;
Stappenbeck, Thaddeus S. ;
Virgin, Herbert W. .
CELL, 2010, 141 (07) :1135-U64
[4]
A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease [J].
Cadwell, Ken ;
Patel, Khushbu K. ;
Komatsu, Masaaki ;
Virgin, Herbert W. ;
Stappenbeck, Thaddeus S. .
AUTOPHAGY, 2009, 5 (02) :250-252
[5]
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation [J].
Cooney, Rachel ;
Baker, John ;
Brain, Oliver ;
Danis, Benedicte ;
Pichulik, Tica ;
Allan, Philip ;
Ferguson, David J. P. ;
Campbell, Barry J. ;
Jewell, Derek ;
Simmons, Alison .
NATURE MEDICINE, 2010, 16 (01) :90-U128
[6]
Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy ANALYSIS OF THE ORGANIZATION OF THE Atg16L1 COMPLEX IN FIBROBLASTS [J].
Fujita, Naonobu ;
Saitoh, Tatsuya ;
Kageyama, Shun ;
Akira, Shizuo ;
Noda, Takeshi ;
Yoshimori, Tamotsu .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (47) :32602-32609
[7]
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations [J].
Hampe, J ;
Cuthbert, A ;
Croucher, PJP ;
Mirza, MM ;
Mascheretti, S ;
Fisher, S ;
Frenzel, H ;
King, K ;
Hasselmeyer, A ;
MacPherson, AJS ;
Bridger, S ;
van Deventer, S ;
Forbes, A ;
Nikolaus, S ;
Lennard-Jones, JE ;
Foelsch, UR ;
Krawczak, M ;
Lewis, C ;
Schreiber, S ;
Mathew, CG .
LANCET, 2001, 357 (9272) :1925-1928
[8]
ATG16L1 and NOD2 Interact in an Autophagy-Dependent Antibacterial Pathway Implicated in Crohn's Disease Pathogenesis [J].
Homer, Craig R. ;
Richmond, Amy L. ;
Rebert, Nancy A. ;
Achkar, Jean-Paul ;
McDonald, Christine .
GASTROENTEROLOGY, 2010, 139 (05) :1630-+
[9]
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease [J].
Hugot, JP ;
Chamaillard, M ;
Zouali, H ;
Lesage, S ;
Cézard, JP ;
Belaiche, J ;
Almer, S ;
Tysk, C ;
O'Morain, CA ;
Gassull, M ;
Binder, V ;
Finkel, Y ;
Cortot, A ;
Modigliani, R ;
Laurent-Puig, P ;
Gower-Rousseau, C ;
Macry, J ;
Colombel, JF ;
Sahbatou, M ;
Thomas, G .
NATURE, 2001, 411 (6837) :599-603
[10]
Host recognition of bacterial muramyl dipeptide mediated through NOD2 [J].
Inohara, N ;
Ogura, Y ;
Fontalba, A ;
Gutierrez, O ;
Pons, F ;
Crespo, J ;
Fukase, K ;
Inamura, S ;
Kusumoto, S ;
Hashimoto, M ;
Foster, SJ ;
Moran, AP ;
Fernandez-Luna, JL ;
Nuñez, G .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (08) :5509-5512