The specification of olfactory neurons

被引:16
作者
Ebrahimi, FAW [1 ]
Chess, A
机构
[1] MIT, Whitehead Inst Biomed Res, Cambridge Ctr 9, Cambridge, MA 02142 USA
[2] MIT, Dept Biol, Cambridge Ctr 9, Cambridge, MA 02142 USA
关键词
D O I
10.1016/S0959-4388(98)80031-7
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Recent studies have shed light on the different relationships between odorant receptor expression and the specification of neural identity in the olfactory systems of vertebrates and invertebrates. In mice, neuronal identity and axon guidance are specified by the single expressed olfactory receptor, whereas in C. elegans, neuronal identity appears to be independent of receptor expression.
引用
收藏
页码:453 / 457
页数:5
相关论文
共 37 条
  • [1] CHEMOSENSORY NEURONS WITH OVERLAPPING FUNCTIONS DIRECT CHEMOTAXIS TO MULTIPLE CHEMICALS IN C-ELEGANS
    BARGMANN, CI
    HORVITZ, HR
    [J]. NEURON, 1991, 7 (05) : 729 - 742
  • [2] Noncoordinate expression of odorant receptor genes tightly linked in the zebrafish genome
    Barth, AL
    Dugas, JC
    Ngai, J
    [J]. NEURON, 1997, 19 (02) : 359 - 369
  • [3] Asynchronous onset of odorant receptor expression in the developing zebrafish olfactory system
    Barth, AL
    Justice, NJ
    Ngai, J
    [J]. NEURON, 1996, 16 (01) : 23 - 34
  • [4] Mice deficient in Golf are anosmic
    Belluscio, L
    Gold, GH
    Nemes, A
    Axel, R
    [J]. NEURON, 1998, 20 (01) : 69 - 81
  • [5] OLFACTORY RECEPTOR GENE-CLUSTER ON HUMAN-CHROMOSOME-17 - POSSIBLE DUPLICATION OF AN ANCESTRAL RECEPTOR REPERTOIRE
    BENARIE, N
    LANCET, D
    TAYLOR, C
    KHEN, M
    WALKER, N
    LEDBETTER, DH
    CARROZZO, R
    PATEL, K
    SHEER, D
    LEHRACH, H
    NORTH, MA
    [J]. HUMAN MOLECULAR GENETICS, 1994, 3 (02) : 229 - 235
  • [6] General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel
    Brunet, LJ
    Gold, GH
    Ngai, J
    [J]. NEURON, 1996, 17 (04) : 681 - 693
  • [7] A NOVEL MULTIGENE FAMILY MAY ENCODE ODORANT RECEPTORS - A MOLECULAR-BASIS FOR ODOR RECOGNITION
    BUCK, L
    AXEL, R
    [J]. CELL, 1991, 65 (01) : 175 - 187
  • [8] Byrd CA, 1996, J NEUROBIOL, V29, P445, DOI 10.1002/(SICI)1097-4695(199604)29:4<445::AID-NEU3>3.0.CO
  • [9] 2-8
  • [10] ALLELIC INACTIVATION REGULATES OLFACTORY RECEPTOR GENE-EXPRESSION
    CHESS, A
    SIMON, I
    CEDAR, H
    AXEL, R
    [J]. CELL, 1994, 78 (05) : 823 - 834