Hyphenation of high-performance liquid chromatography (HPLC) and other chromatographic techniques (SFC, GPC, GC, CE) with nuclear magnetic resonance (NMR): A review

The development of the hyphenation of high-performance liquid chromatography (HPLC) and other chromatographic methods (supercritical fluid chromatography (SFC), gel-permeation chromatography (GPC), gas chromatography (GC) and capillary electrophoresis (CE)) with nuclear magnetic resonance (NMR) is reviewed. The focus is not only on application (e.g. pharmaceutical chemistry, food chemistry, polymer analysis, fuel chemistry), but also on technical improvements (e.g. flow rate, flow cell, probe, solvent suppression). The increasing importance and overwhelming analytical possibilities of on-line coupling of HPLC with NMR is demonstrated. The literature up to March 1995 is considered.